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Traitorous Tumor Cells Kill Their Own Kind

Using cancer to fight cancer might seem counterintuitive, but there’s method to the apparent madness and, according to proof-of-principle animal experiments reported in Science Translational Medicine today (July 11), it works. Tumor cells engineered to secrete anticancer agents yet resist self-destruction can be used to kill tumors in mice and then, in a fate befitting this act …

FDA Approves First Marijuana-Derived Drug

he US Food and Drug Administration today (June 25) approved for the first time a marijuana-derived drug, Epidiolex, for the treatment of two rare forms of epilepsy. The drug contains cannabidiol, or CBD, and does not make users high while reducing the rate of seizures in patients with Dravet or Lennox-Gastaut syndromes, clinical trials show.

Opinion: No, AI Will Not Replace Radiologists

Mutaz Musa’s recent opinion piece in The Scientist predicts that AI will replace radiologists as interpreters of medical images. As a radiologist for the past 38 years, I disagree. It is impossible for me to argue that AI software will never (as in, within millennia) be able to perform at a human level. Instead, I will argue a much more tightly …

Questions Raised About “Breakthrough” Therapies’ Clinical Support

The US Food and Drug Administration’s “breakthrough therapy” designation has helped expedite the development and approval of more than 45 therapeutics in the last 5 years. But a study published in JAMA today (July 17) suggests that these interventions gain Food and Drug Administration (FDA) approval on the basis of weaker clinical evidence than those that don’t …